ISSN: 1308-0954
Dil: Türkçe
İçerik: Özel sayılar şeklinde yayınlanır.
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Diabetes Mellitus: Bone And Joints
Dr. Ayşe A. KÜÇÜKDEVECİ,a Dr. Pınar BAŞARANa
aFiziksel Tıp ve Rehabilitasyon AD, Ankara Üniversitesi Tıp Fakültesi, ANKARA
Musculoskeletal system is affected in a variety of ways in diabetes mellitus. Metabolic perturbations such as glycosylation of proteins, microvascular abnormalities, collagen accumulation in skin and periarticular tissues can affect connective tissue and give rise to various disorders involving muscles, bone and joints. In some of these disorders or complications there is a direct cause-and-effect relation with diabetes mellitus whereas in others only an epidemiologic association is reported without any proven cause-and effect relationship. Main musculoskeletal disorders seen in diabetes mellitus are limited joint mobility syndrome, Dupuytren’s contracture, adhesive capsulitis, flexor tenosynovitis, hyperosteosis, carpal tunnel syndrome, neuropathic arthropathy, diabetic amyotrophy, diabetic muscle infarct, osteoporosis and osteoarthritis. These disorders will be reviewed within the context of etiopathogenesis, clinical findings and treatment approaches.Keywords: Diabetes mellitus, bone and bones, joints, musclesTurkiye Klinikleri J Endocrin-Special Topics 2008, 1(1):56-63
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